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Austin Murphy
Austin Murphy

Jennifers Life [v0.4]

From May through October 2019, a life-size version of ADRIFT was featured in the exhibition 'Hedonism' at MOD. museum at University of South Australia, allowing museum visitors to interact with the game in "real-life".

Jennifers Life [v0.4]

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It is noteworthy that the largest sponges were observed only within the central regions of the seamount peaks, where deposits of siboglinid tubes were observed and were always associated with substantial spicule abundances. The spicule-tube mat extended beyond this seamount central region of high sponge coverage, though as a thinner layer with far less sponge spicule inclusion. Across this exposed substrate individual sponges seemed to actively crawl on top of the spicule-tube mat, leaving behind abundant and visible spicule trails81. Although sponges are generally considered sessile organisms in adult life, locomotion has been observed in few species and attributed to be a response to food availability and/or population density82. We suggest that this mobility behavior facilitates foraging, whilst simultaneously promoting localized detrital accumulation for later utilization by the sponges. With movement, these sponges deposit large numbers of spicules which form the dense mat-like structure so prevalent on the Langseth Ridge peaks. These spicules are locally integrated with the fossil detritus from the extinct hydrothermal ecosystem, increasing seafloor rugosity and roughness and therefore promoting the local settling of particles and biogenic materials, then subsequently hydrodynamically entrapping this material in the complex mat matrix. This mat can build up to decimeter thickness over time. The OM trapped in this complex mat matrix, including sediment-borne bacteria, may at times be remixed through sediment resuspension by bottom water currents. Such deposit mixing was previously observed along continental shelf edges67,83,84. However, in the studied open ocean seamount area, the sluggishness of the bottom current may make such remixing a rare occasion22,38. The observed repositioning of the sponges may potentially facilitate their access to recently integrated detrital matter with this movement also potentially increasing the flux of small particles and microbially hydrolyzed DOM to the sponges33,34, which can then be used by the holobionts.

MSEW mice also had a greater abundance of Peptostreptococcacea, which is a family of strict anaerobes that is associated with colorectal cancer (61, 62). In a mouse model of dextran sulfate sodium (DSS)-induced colitis, chronic stress caused a proliferation of Peptostreptococcacea and degradation of the colonic mucus barrier (7). An enrichment of Peptostreptococcacea in MSEW mice may be an indication of a proinflammatory environment and warrants further investigation.

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Retired Special Forces Maj. Ian Fishback was a whistleblower on torture by the U.S. military who graduated at the top of his class at West Point. He died at 42, broke and medicated with antipsychotic drugs in an adult foster care center as family and friends sought mental health care for him. Fishback was deployed to Afghanistan and Iraq with the Army's 82nd Airborne Division. In Iraq, he saw troops using "enhanced interrogation" tactics such as breaking prisoners' bones, and began protesting up the chain of command. Fishback later met with Sen. John McCain, who was tortured during the Vietnam War, and many other members of Congress, meetings that were credited with helping to pass McCain's Detainee Treatment Act of 2005, as NPR's Quil Lawrence reported. Fishback's sister said he stood by doing "what's right regardless of the cost" his entire life.

Vicente Fernández was considered the last living legend of Mexican ranchera, a style of music rooted in the traditions of rural Mexican life. He released dozens of albums and won three Grammys, performing in large arenas as well as bullrings and cockfight pits. Accompanied by a full mariachi ensemble, Fernández, who died at 81, sang about honor and courtship, cockfights and rodeos, love and heartbreak. He was an icon for Mexican immigrants to the U.S. and around the world, his music transporting them to "the ranches and towns they'd reluctantly left behind in search of opportunity abroad," as NPR's Adrian Florido wrote.

Using a split-brood design, offspring from 18 females of an orb-web spider were subjected to two treatments that differed in the amount of light provided during 12hours of dark. Spiders either received 0 or 20 lux during the night and were raised from egg to adult. Growth and development of 440 individuals were carefully monitored and the number of moulting events was documented. Prey availability was standardised and increased twice throughout development to accommodate increasing demands. The experiment was designed to test the hypothesis that artificial light at night (ALAN) would affect survival and life-history as well as female fecundity. The experimental design varies a single variable (light at night) on two levels. A more complex design might have been valuable, as for example two levels of prey supply. Perhaps this could be planned as a follow-up?

Although I have enjoyed reading your article and I think you present very interesting and strong results, I was also slightly disappointed in that I thought that you had the possibility of a much deeper insight into the effects of light at night on life-histories and fitness, by linking these data to more mechanistic/physiological aspects that might have helped you to explain your results. in the end, these data is very cool and convincing but I miss a clear explanation of how light at night affects maturation time, survival, body mass and reproductive success. Also, how likely is that spiders are exposed to such high levels of LaN in nature? 20 lux is dim, but still in the higher range of what animals can be exposed to in light polluted areas, particularly for mobile animals such as spiders. Also, the explanation for the earlier maturation time is not really comprehensive. What do the authors really think is happening? Do you think that spiders perceive a longer photoperiod, therefore being "tricked" into thinking that it is late in the season and they need to speed up their maturation if they want to be ready at the right time, or perhaps something more fundamental about the circannual and circadian rhythms of these animals is modified? For instance, see Wikelski et al 2008 Phil Trans B for a very interesting take into how different photoperiod might affect energy turnover which in turn might affect the speed of the circannual clock. in general, I think a more fundamental understanding of the mechanisms at play might have made this article much more compelling. But I do like it still!

Abstract:Mature and stable intestinal microbiota in chickens is essential for health and production. Slow development of microbiota in young chickens prolongs the precarious period before reaching mature configuration. Whether probiotics can play a role in the early maturation of intestinal microbiota is unknown. To address this, day-old chicks were assigned into six groups: NC (basal diet), PC (virginiamycin), low (BPL) and high-dose (BPH) of Bacillus pumilus, and low (BSL) and high-dose (BSH) of Bacillus subtilis. Cecal contents at days 7, 14, 28 and 42 were used to analyze the treatment and time effects on the diversity and composition of microbiota. Overall, the alpha diversity was significantly decreased in the NC group between days 7 and 14, while this decline was prevented in the Bacillus subtilis probiotic (BSL and BSH) and even reversed in the BPH group. The beta-diversity showed significant responses of microbial communities to probiotics in first two weeks of life. Analyses of the abundance of microbiota reflected that members of the family Ruminococcaceae (Ruminnococcus, Oscillospira, Faecalibacterium, Butyricicoccus, and Subdoligranulum), which were dominant in mature microbiota, were significantly higher in abundance at day 14 in the probiotic groups. Conversely, the abundance of genera within the family Lachnospiraceae (Ruminococcus, Blautia, and Coprococcus) was dominant in early dynamic microbiota but was significantly lower in the probiotic groups at day 14. The Lactobacillus and Bifidobacterium abundance was higher, while the Enterobacteriaceae abundance was lower in the probiotic groups. In summary, the probiotics efficiently helped the cecal microbiota reach mature configuration earlier in life. These results could be used for the future manipulation of microbiota from the perspective of improving poultry performance.Keywords: probiotics; microbiome; maturity; Bacillus subtilis; Bacillus pumilus; gut microbiota; Ruminococcaceae; Lachnospiraceae

The aim of this study was to quantify the value of conducting additional research and reducing uncertainty regarding the cost effectiveness of allopurinol and febuxostat for the management of gout. We used a Markov model that evaluated the cost effectiveness of nine urate-lowering strategies over the lifetime of a hypothetical gout patient. 041b061a72

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